Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

119,90 €


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Información del producto

ISBN9783030495305
EditorialSpringer Nature Switzerland AG
Precio (sin IVA)113,11 €
Impuestos6,79 €
Precio (IVA incluido)119,90 €
Disponibilidad1 Unidad En almacén externo

Descripción del producto

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.